Mitral Valve Prolapse Information

What is Mitral Valve Prolapse?

Located between the upper left chamber and lower left chamber of the heart, the mitral valve is made of two flaps of tissue that normally open and close in a rhythmic way to allow blood to flow in one direction--from the atrium (upper chamber) to the ventricle (lower champer). The left ventricle is responsible for much of the heart's pumping and propels oxygen-rich blood into the arteries. The arteries then carry the blood throughout the body. When the mitral valve doesn't open and close properly, the flaps may "billow" backward slightly into the upper chamber during the heart's contraction (fig. B). This is called mitral valve prolapse (MVP). As a result of MVP, a clicking sound can often be heard by the doctor listening to the heart sounds with a stethoscope.

In MVP, sometimes small amounts of blood may leak backward into the upper chamber of the heart because the valve does not close normally. This causes a "heart murmur," although the heart itself is working normally. The heart has an adequate blood supply, even with the MVP. Prolapsing mitral valves do not usually get worse over time.

Mitral valve prolapse is the most common cardiac problem and may affect five to twenty percent of the population. The condition is most common in women, although men are also affected. With MVP, symptoms do not begin before the early teenage years (approximately age 14 in girls and 15 in boys), but adults of any age may be affected. MVP tends to run in families, so those with blood relatives with MVP have a greater chance of also having the condition. The mitral valve prolapse syndrome is sometimes called dysautonomia. Click here to learn more about dysautonomia.

Physical Findings Unique to the Mitral Valve Prolapse (MVP) Syndrome

Late systolic click and/or a late systolic murmur

Antibiotic Information

In April, 2007 The American Heart Association changed the recommendations regarding the use of antibiotics by Mitral Valve Prolapse patients prior to dental procedures. Preventive antibiotics before a dental procedure are advised for patients with:

  • artificial heart valves
  • a history of having had infective endocarditis
  • certain specific, serious congenital (present from birth) heart conditions, including:
    • unrepaired or incompletely repaired cyanotic congenital heart disease, including those with palliative shunts and conduits
    • a completely repaired congenital heart defect with prosthetic material or device, whether placed by surgery or by catheter intervention, during the first six months after the procedure
    • any repaired congenital heart defect with residual defect at the site or adjacent to the site of a prosthetic patch or a prosthetic device
    • a cardiac transplant which develops a problem in a heart valve.

“Except for the conditions listed above, antibiotic prophylaxis is no longer recommended for any other form of congenital heart disease,” the statement said.

Full statement available by clicking here


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The Autonomic Disorders/MVP Center
880 Montclair Road, Suite 370
Birmingham, AL 35213

Phone: (205) 592-5765
Toll Free: (800) 541-8602
Fax: (205) 592-5707